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Reduced level of alertness at discharge from the hospital in 19%of patients;seizures in 15%(70%focal);severe hypotonia in 11%before surgery, and in 7%at discharge from hospital;generalized pyramidal findings in six (7%);asymmetry of tone in 5%;and chorea that did not persist in 11%. Results of cranial ultrasound tests were abnormal in 20%of patients.Of these those with abnormal cranial ultrasound examinations 55%were abnormal before surgery.Overall mortality was 18%.Of the patients who died,59%had interrupted aortic arch or hypoplastic left heart syndrome.Mortality for patients with these lesions was 40%.Alertness(P=.005),chorea(P=.03)and hypotonia(P=.02)were associated with duration of deep hypothermia longer than 60 minutes.No association was found among other outcomes and study variables,except the relation between severe left-sided heart lesions and mortality.Mortality and neurologic morbidity after open heart surgery on young infants may be due to several factors,including type of lesion, preexisting brain abnormalities,duration of deep hypothermia and strokes. |
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cardiac surgery,hypothermia and circulatory arrest for
cardiac surgery,neurologic complications with
cerebrovascular accident
cerebrovascular accident,infancy and childhood
children
chorea
congenital heart disease
fetus
hypothermia
hypotonia
mortality
postoperative neurologic complications
prognosis
seizure
ultrasonography
ultrasonography,head
ultrasonography,head,fetus-neonate
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